I think backwards compatible support for Wrath of Cortex and Twinsanity is the most we'll get out of Twinsanity, if anything the next game will likely be a direct sequel to Wrath of Cortex, Warped, or CTR that follows a slightly different timeline than Twinsanity. Even if it means a second game as DLC that ends up being packaged with later physical editions of the next game.
Twinsanity's Walrus Chase level needs 12 extra lives right before the Walrus chase level. And that alone makes the game annoying enough to be worth only paying $9 Canadian
